{"id":46488,"date":"2021-12-30T14:43:10","date_gmt":"2021-12-30T06:43:10","guid":{"rendered":"https:\/\/www.medtecs.com\/?p=46488"},"modified":"2022-02-08T12:40:30","modified_gmt":"2022-02-08T04:40:30","slug":"how-does-the-immune-system-fight-virus-including-covid19","status":"publish","type":"post","link":"https:\/\/www.medtecs.com\/zh\/how-does-the-immune-system-fight-virus-including-covid19\/","title":{"rendered":"\u514d\u75ab\u7cfb\u7d71\u5982\u4f55\u5c0d\u6297\u51a0\u72c0\u75c5\u6bd2\u7b49\u5165\u4fb5\u8005?"},"content":{"rendered":"<p>\u514d\u75ab\u7cfb\u7d71\u5982\u4f55\u5c0d\u6297\u51a0\u72c0\u75c5\u6bd2?<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u6297\u9ad4\u7684\u7522\u751f\u662f\u5c0d\u75c5\u6bd2\u3001\u7d30\u83cc\u6216\u5176\u4ed6\u75c5\u539f\u9ad4\u7684\u91cd\u8981\u514d\u75ab\u53cd\u61c9\uff0c\u4f46\u9019\u4e26\u4e0d\u662f\u8eab\u9ad4\u5c0d\u6297\u611f\u67d3\u7684\u552f\u4e00\u65b9\u5f0f\u3002<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u75ab\u82d7\u52a0\u5f37\u5291\u662f\u589e\u5f37\u5c0d SARS-CoV-2\u514d\u75ab\u4fdd\u8b77\u7684\u4e00\u7a2e\u65b9\u5f0f\u3002<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>\u4e00\u4e9b\u5c08\u5bb6\u8cea\u7591\u662f\u5426\u6709\u5fc5\u8981\u65bd\u6253\u52a0\u5f37\u5291\uff0c\u6211\u5011\u7684\u514d\u75ab\u7cfb\u7d71\u4e5f\u8a31\u5728\u65bd\u6253\u5169\u5291\u5f8c\u5df2\u8db3\u5920\u5f37\u5927\uff0c\u4e3b\u5f35\u4e0d\u9700\u984d\u5916\u7684\u75ab\u82d7\u5291\u91cf\u3002<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u96a8\u8457\u5404\u570b\u63a8\u51fa\u52a0\u5f37\u5291\u91cf\u7684 COVID-19 \u75ab\u82d7\uff0c\u95dc\u65bc\u73fe\u5728\u662f\u5426\u9700\u8981\u9019\u4e9b\u984d\u5916\u63aa\u65bd\u7684\u8a0e\u8ad6\u96c6\u4e2d\u5728\u4e09\u500b\u8b70\u984c\u4e0a\uff0d\u7a81\u7834\u6027\u611f\u67d3\uff08\u6307<\/span><span style=\"font-weight: 400;\">\u65bd\u6253\u75ab\u82d7\u5f8c\u537b\u4f9d\u7136\u78ba\u8a3a\u7684\u60c5\u6cc1\uff09<\/span><span style=\"font-weight: 400;\">\u3001\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\u548cDelta\u8b8a\u7570\u682a\u7684\u885d\u64ca\uff0c\u7576\u7136\uff0c\u9019\u4e9b\u90fd\u662f\u76f8\u4e92\u95dc\u806f\u7684\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u7522\u751f\u6297\u9ad4\uff0c\u53ea\u662f\u514d\u75ab\u7cfb\u7d71\u7528\u4f86\u5c0d\u6297\u611f\u67d3\u7684\u5176\u4e2d\u4e00\u7a2e\u65b9\u5f0f\u3002\u82e5\u6211\u5011\u53ea\u95dc\u6ce8\u6297\u9ad4\u6c34\u6e96\u7684\u8b70\u984c\uff0c\u6703\u907a\u6f0f\u5176\u4ed6\u90e8\u5206\u63d0\u4f9b\u7684\u4fdd\u8b77\u529b\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5118\u7ba1\u5982\u6b64\uff0c\u4e86\u89e3\u6297\u9ad4\u7684\u4fdd\u8b77\u539f\u7406\u4ee5\u53ca\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\u5c0d\u65bc\u9810\u9632\u65b0\u51a0\u80ba\u708e\u7684\u5f71\u97ff\u4ecd\u7136\u5f88\u91cd\u8981\u3002<\/span><\/p>\n<h2><b>\u4ec0\u9ebc\u662f\u6297\u9ad4\uff1f<\/b><\/h2>\n<p>&nbsp;<\/p>\n<blockquote><p><span style=\"font-weight: 400;\">\u6297\u9ad4<\/span><span style=\"font-weight: 400;\">\u53c8\u7a31<\/span><b>\u514d\u75ab\u7403\u86cb\u767d\uff0c<\/b><span style=\"font-weight: 400;\">\u662f\u514d\u75ab\u7cfb\u7d71\u5728\u4eba\u9ad4\u906d\u75c5\u6bd2\u611f\u67d3\u6642\u7522\u751f\u7684Y\u5f62\u86cb\u767d\u8cea\u3002\u5b83\u5011\u8b58\u5225\u4e26\u7d50\u5408\u7279\u5b9a\u7684\u5206\u5b50\u7d50\u69cb\uff08\u7a31\u70ba\u6297\u539f\uff09\uff0c\u5982\u75c5\u6bd2\u6216\u7d30\u83cc\u8868\u9762\u7684\u5206\u5b50\u7d50\u69cb\u3002<\/span><\/p><\/blockquote>\n<p><span style=\"font-weight: 400;\">\u6297\u9ad4\u662f\u7531B\u7d30\u80de\uff08\u4e00\u7a2e\u514d\u75ab\u7d30\u80de\uff09\u7522\u751f\uff0c\u5b58\u5728\u65bc\u8840\u6db2\u3001\u6dcb\u5df4\u7d50\u3001\u813e\u81df\u548c\u5176\u4ed6\u7d44\u7e54\u4e2d\uff0c\u6bcf\u500bB\u7d30\u80de\u6703\u7522\u751f\u4e00\u7a2e\u7279\u5b9a\u985e\u578b\u7684\u6297\u9ad4\u3002\u79d1\u5b78\u5bb6\u5011<\/span><a href=\"https:\/\/www.nature.com\/articles\/s41586-019-0879-y\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u4f30\u8a08<\/span><\/a><span style=\"font-weight: 400;\">\u4eba\u985e\u514d\u75ab\u7cfb\u7d71\u53ef\u4ee5\u7522\u751f\u81f3\u5c11\u4e00\u842c\u5104\u7a2e\u7368\u7279\u7684\u6297\u9ad4\u3002\u7576\u8eab\u9ad4\u7b2c\u4e00\u6b21\u9047\u5230\u75c5\u6bd2\u6216\u5176\u4ed6\u75c5\u539f\u9ad4\u6642\uff0cB \u7d30\u80de\u53ef\u4ee5\u8207\u8a72\u75c5\u539f\u9ad4\u7d50\u5408\uff0cB\u7d30\u80de\u5c07\u6703\u88ab\u6d3b\u5316\u3002\u4e00\u65e6\u88ab\u6d3b\u5316\uff0cB \u7d30\u80de\u5c31\u6703\u589e\u6b96\u4e26\u5f62\u6210\u4e0d\u540c\u7684\u7d30\u80de\uff0c\u5305\u62ec\u6f3f\u7d30\u80de\uff0c\u5b83\u5011\u662f\u7522\u751f\u6297\u9ad4\u7684\u300c\u5de5\u5ee0\u300d\u3002<\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.medtecs.com\/wp-content\/uploads\/antibody-schematic-diagram-medtecs-group.jpg\" alt=\"\" \/><\/p>\n<p><span style=\"font-weight: 400;\">\u6297\u9ad4\u5728\u611f\u67d3\u5f8c\u6703\u5728\u9ad4\u5167\u4fdd\u7559\u4e00\u6bb5\u6642\u9593\uff0c\u4f46\u5b83\u5011\u7684\u6578\u91cf\u6703\u5728\u6578\u6708\u6216\u6578\u5e74\u5167\u6e1b\u5c11\uff0c\u5be6\u969b\u4e0a\u6703\u53d6\u6c7a\u65bc\u75c5\u539f\u9ad4\u548c\u5176\u4ed6\u56e0\u7d20\u3002<\/span><\/p>\n<h2><b>\u75ab\u82d7\u7684\u539f\u7406\u662f\u4ec0\u9ebc\uff1f<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u75ab\u82d7\u6703\u89f8\u767c\u985e\u4f3c\u4eba\u9ad4\u9047\u5230\u75c5\u6bd2\u6642\u7684\u514d\u75ab\u53cd\u61c9\uff0c\u6240\u4ee5\u4e0d\u6703\u50cf\u81ea\u7136\u611f\u67d3\u90a3\u6a23\u7522\u751f\u56b4\u91cd\u75c5\u75c7\u3002<\/span><span style=\"font-weight: 400;\">\u300c\u75ab\u82d7\u63a5\u7a2e\u300d\u57fa\u672c\u4e0a\u662f\u4e00\u7a2e\u70ba\u8eab\u9ad4\u63d0\u4f9b\u6297\u9ad4\u7684\u6280\u5de7\uff0c\u6240\u4ee5\u7576\u4f60\u771f\u7684\u4e0d\u5e78\u63a5\u89f8\u5230\u75c5\u6bd2\u6642\uff0c\u4f60\u81f3\u5c11\u6709\u6297\u9ad4\u8ecd\u968a\u53ef\u4ee5\u62b5\u6297\u3002<\/span><span style=\"font-weight: 400;\"><strong>mRNA<\/strong>\u75ab\u82d7\u5247\u91dd\u5c0d\u6211\u5011\u7684\u7d30\u80de\u5982\u4f55\u88fd\u9020\u91dd\u5c0d\u51a0\u72c0\u75c5\u6bd2\u523a\u7a81\u86cb\u767d\u7684\u6297\u9ad4\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>\u6211\u5011\u9700\u8981\u591a\u9ad8\u7684\u6297\u9ad4\u6578\uff1f<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u514d\u75ab\u7cfb\u7d71\u4e0d\u6703\u53ea\u7522\u751f\u4e00\u7a2e\u6297\u9ad4\u4f86\u62b5\u6297\u75c5\u539f\u9ad4\uff0c\u800c\u662f\u7522\u751f\u591a\u7a2e\u4e0d\u540c\u7684\u6297\u9ad4\u3002\u9019\u4e9b\u6297\u9ad4\u4e2d\u67d0\u4e9b\u6703\u8207\u6297\u539f\u5f37\u70c8\u7d50\u5408\uff0c\u800c\u53e6\u4e00\u4e9b\u5247\u4e0d\u7136\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5b83\u5011\u4e5f\u53ef\u5206\u70ba\u4e2d\u548c\u6297\u9ad4\u548c\u975e\u4e2d\u548c\u6297\u9ad4\u3002\u9867\u540d\u601d\u7fa9\uff0c\u4e2d\u548c\u6297\u9ad4\u53ef\u4ee5\u300c\u4e2d\u548c\u300d\u75c5\u539f\u9ad4\u3002\u8209\u500b\u4f8b\u5b50\uff1a\u70ba\u4e86\u5c0d\u4ed8 <strong>SARS-CoV-2<\/strong>\uff0c\u67d0\u4e9b\u4e2d\u548c\u6297\u9ad4\u6703\u8207\u51a0\u72c0\u75c5\u6bd2\u523a\u7a81\u86cb\u767d\u7dca\u5bc6\u7d50\u5408\uff0c\u9632\u6b62\u5b83\u611f\u67d3\u5176\u4ed6\u7d30\u80de\u3002\u96d6\u7136\u975e\u4e2d\u548c\u6297\u9ad4\u4e0d\u6703\u9019\u6a23\u505a\uff08\u6216\u53ea\u662f\u5f88\u5fae\u5f31\uff09\u5b83\u5011\u4ecd\u7136\u53ef\u4ee5\u5728\u5c0d\u6297\u75c5\u539f\u9ad4\u9019\u65b9\u9762\u767c\u63ee\u4f5c\u7528\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u975e\u4e2d\u548c\u6297\u9ad4\u4e0d\u80fd\u4fdd\u8b77\u7d30\u80de\u514d\u53d7\u611f\u67d3\uff0c\u4f46\u5b83\u53ef\u4ee5\u8b58\u5225\u90a3\u4e9b\u53d7\u611f\u67d3\u4e4b\u7d30\u80de\u8868\u9762\u7684\u75c5\u6bd2\u6297\u539f\u3002\u7576\u975e\u4e2d\u548c\u6297\u9ad4\u8207\u9019\u4e9b\u8868\u9762\u6297\u539f\u7d50\u5408\u6642\uff0c\u514d\u75ab\u7cfb\u7d71\u7684\u5176\u4ed6\u90e8\u5206\u5c31\u6703\u958b\u59cb\u4f5c\u7528\uff0c\u4e26\u6e05\u9664\u90a3\u4e9b\u53d7\u611f\u67d3\u7684\u7d30\u80de\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/fhs.um.edu.mo\/en\/\" target=\"_blank\" rel=\"noopener\">Faculty of Health Sciences and an Associate Faculty<\/a>\u7684\u91ab\u751fPantophlet\u8868\u793a\uff0c\u5c0d\u65bc<strong>COVID-19<\/strong>\uff0c\u5927\u591a\u6578\u5be6\u9a57\u5ba4\u90fd\u6703\u6e2c\u91cf\u4e2d\u548c\u6297\u9ad4\uff0c\u56e0\u70ba\u9019\u53ef\u4ee5\u70ba\u4eba\u985e\u63d0\u4f9b\u5408\u7406\u7684\u4fdd\u8b77\u63aa\u65bd\uff08\u9632\u6b62\u611f\u67d3\uff09\u3002\u7136\u800c\uff0c\u5c0d\u65bc<strong> COVID-19<\/strong>\u6211\u5011\u9084\u4e0d\u6e05\u695a\u9700\u8981\u591a\u9ad8\u7684\u4e2d\u548c\u6297\u9ad4\u6c34\u6e96\u624d\u80fd\u63d0\u4f9b\u4e00\u5b9a\u7684\u9810\u9632\u6548\u679c\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u7f85\u683c\u65af\u516c\u5171\u885b\u751f\u5b78\u9662(<a href=\"https:\/\/sph.rutgers.edu\" target=\"_blank\" rel=\"noopener\">Rutgers &#8211; School of Public Health<\/a>)<\/span><span style=\"font-weight: 400;\">\u751f\u7269\u7d71\u8a08\u5b78\u548c\u6d41\u884c\u75c5\u5b78\u526f\u6559\u6388 <a href=\"https:\/\/eohsi.rutgers.edu\/eohsi-directory\/name\/emily-barrett\/\" target=\"_blank\" rel=\"noopener\">Emily S. Barrett<\/a> \u535a\u58eb\u8aaa\u660e\uff1a\u300c\u6b32\u78ba\u5b9a\u9019\u7a2e\u6700\u4f4e\u9650\u5ea6\u7684\u514d\u75ab\u53cd\u61c9\uff0c\u904e\u7a0b\u975e\u5e38\u8907\u96dc\uff0c\u56e0\u70ba\u9664\u4e86\u6297\u9ad4\u4e4b\u5916\uff0c\u514d\u75ab\u7cfb\u7d71\u9084\u6709\u5176\u4ed6\u4fdd\u8b77\u4eba\u9ad4\u7684\u65b9\u5f0f\u3002\u9019\u5305\u62ec\u7d30\u80de\u6216 T \u7d30\u80de\u4ecb\u5c0e\u7684\u514d\u75ab\u53cd\u61c9\u3002\u6240\u4ee5\u96d6\u7136\u6211\u5011\u90fd\u60f3\u78ba\u5b9a\u4e00\u500b\u6578\u5b57\u505a\u70ba\u9580\u6abb\uff0c\u4f46\u76ee\u524d\u6c92\u6709\u660e\u78ba\u7684\u7b54\u6848\u3002\u300d\u78ba\u5b9a\u7684\u662f\uff0c\u96a8\u8457\u4e2d\u548c\u6297\u9ad4\u6c34\u5e73\u7684\u4e0b\u964d\uff0c\u767c\u751f\u7a81\u7834\u6027\u611f\u67d3\u7684\u53ef\u80fd\u6027\u66f4\u5927\u3002<\/span><\/p>\n<h2><b>\u514d\u75ab\u53cd\u61c9\u56e0\u4eba\u800c\u7570<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u5118\u7ba1\u79d1\u5b78\u5bb6\u5011\u7d93\u5e38\u95dc\u6ce8\u75ab\u82d7\u6709\u6548\u6027\uff0c\u4f46\u4eba\u5011\u5c0d\u75ab\u82d7\u63a5\u7a2e\u548c\u81ea\u7136\u611f\u67d3\u7684\u514d\u75ab\u53cd\u61c9\u53ef\u80fd\u90fd\u6703\u6709\u6240\u4e0d\u540c\uff0c\u6709\u6642\u5dee\u7570\u5f88\u5927\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5728\u4e00\u9805<\/span><a href=\"https:\/\/academic.oup.com\/jid\/advance-article\/doi\/10.1093\/infdis\/jiab411\/6350267\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u7814\u7a76\u4e2d<\/span><\/a><span style=\"font-weight: 400;\">\uff0c\u5be6\u9a57\u4eba\u54e1\u767c\u73fe\uff0c\u5927\u591a\u6578\u7814\u7a76\u53c3\u8207\u8005\u5728\u611f\u67d3\u5f8c\u7684 6 \u500b\u6708\u5167\u90fd\u5177\u6709\u6301\u7e8c\u6027\u7684\u6297\u9ad4\uff0c\u4f46\u5728\u6b64\u671f\u9593\uff0c\u6839\u64da\u75c7\u72c0\uff0c\u6c34\u6e96\u7684\u5347\u9ad8\u7a0b\u5ea6\u6709\u6240\u4e0d\u540c\u3002\u75c7\u72c0\u56b4\u91cd\u7684\u4eba\u5728\u524d 2 \u500b\u6708\u5167\u6297\u9ad4\u6c34\u6e96\u6025\u5287\u4e0a\u5347\uff0c\u800c\u7121\u75c7\u72c0\u611f\u67d3\u8005\u5728 6 \u500b\u6708\u5167\u6297\u9ad4\u6c34\u6e96\u7de9\u6162\u589e\u52a0\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u7814\u7a76\u4eba\u54e1\u4e26\u6c92\u6709\u7814\u7a76\u6297\u9ad4\u6c34\u6e96\u8f03\u9ad8\u7684\u4eba\u662f\u5426\u80fd\u9632\u6b62\u518d\u6b21\u611f\u67d3\u3002\u4f46\u662f\u5728\u7d55\u5927\u591a\u6578\u53d7\u611f\u67d3\u7684\u500b\u9ad4\u4e2d\u90fd\u53ef\u4ee5\u6aa2\u6e2c\u5230\u6297\u9ad4\uff0c\u4e26\u4e14\u4e0d\u9700\u8981\u9ad8\u5faa\u74b0\u6297\u9ad4\u8a08\u6578\u5c31\u80fd\u89c0\u5bdf\u5230\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u53e6\u4e00\u9805<\/span><a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/Spectrum.00087-21\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u7814\u7a76<\/span><\/a><span style=\"font-weight: 400;\">\u767c\u73fe\uff0c\u5373\u4f7f\u662f\u8f15\u75c7\u60a3\u8005\uff0c\u4f3c\u4e4e\u4e5f\u80fd\u9810\u9632\u518d\u6b21\u611f\u67d3\uff0c\u81f3\u5c11\u5728\u611f\u67d3\u5f8c\u7684 6 \u500b\u6708\u5167\u662f\u9019\u6a23\u3002\u7576\u8ac7\u5230\u63a5\u7a2e\u75ab\u82d7\u5f8c\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\uff0c\u4e00\u9805<\/span><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2021.08.15.21262067v3.full.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u7814\u7a76<\/span><\/a><span style=\"font-weight: 400;\">\u8868\u660e\uff0c\u4e0d\u540c\u7684\u7fa4\u9ad4\u4e5f\u51fa\u73fe\u4e86\u985e\u4f3c\u7684\u73fe\u8c61\u3002\u7814\u7a76\u4eba\u54e1\u7814\u7a76\u4e86 120 \u540d\u7642\u990a\u9662\u5c45\u6c11\u548c 92 \u540d\u63a5\u53d7\u904e 2 \u5291<strong>\u8f1d\u745e-BioNTech COVID-19<\/strong> \u75ab\u82d7\u7684\u91ab\u8b77\u4eba\u54e1\u7684\u8840\u6db2\u6a23\u672c\u30026 \u500b\u6708\u5f8c\uff0c\u5169\u7d44\u7684\u6297\u9ad4\u6c34\u6e96\u5747\u4e0b\u964d\u4e86 84% \u4ee5\u4e0a\u3002\u7814\u7a76\u4eba\u54e1\u9084\u767c\u73fe\uff0c\u8207\u672a\u611f\u67d3\u7684\u4eba\u76f8\u6bd4\uff0c\u4e4b\u524d\u611f\u67d3\u904e\u51a0\u72c0\u75c5\u6bd2\u7684\u4eba\u7684\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\u5e45\u5ea6\u76f8\u4f3c\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u7136\u800c\uff0c\u672a\u611f\u67d3\u904e\u7684\u8001\u5e74\u4eba\u5c0d\u75ab\u82d7\u63a5\u7a2e\u7522\u751f\u7684\u539f\u59cb\u6297\u9ad4\u53cd\u61c9\u8f03\u5c11\u3002\u9019\u7a2e\u8f03\u4f4e\u7684\u514d\u75ab\u53cd\u61c9\u4e5f\u767c\u751f\u5728\u5176\u4ed6\u75ab\u82d7\u4e2d\uff0c\u5305\u62ec\u5b63\u7bc0\u6027\u6d41\u611f\u75ab\u82d7\u3002\u9019\u662f\u4ee5\u63a5\u7a2e\u8005\u7684\u5e74\u9f61\u4f5c\u70ba\u8b8a\u6578\u7684\u7814\u7a76\u3002\u7814\u7a76\u4f5c\u8005\u3001<\/span><a href=\"https:\/\/case.edu\/medicine\/bstp\/research\/trainers-directory?combine=&amp;page=2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u51f1\u65af\u897f<\/span><\/a><span style=\"font-weight: 400;\">\u91ab\u5b78\u9662\u6559\u6388\u6234\u7dad\u00b7\u52a0\u62ff\u5927\u8fea (David Canaday) \u535a\u58eb\u8868\u793a\uff0c\u63a5\u7a2e\u75ab\u82d7\u5f8c 6 \u500b\u6708\uff0c\u9019\u4e9b\u7642\u990a\u9662\u5c45\u6c11\u4e2d\u6709 70% \u7684\u300c\u4e2d\u548c\u6297\u9ad4\u6c34\u6e96\u300d\u975e\u5e38\u4f4e\uff0c\u8655\u65bc\u6aa2\u6e2c\u6975\u9650\u3002\u4e0d\u904e\u8a72\u7814\u7a76\u5c1a\u672a\u7d93\u904e\u540c\u884c\u8a55\u5be9\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u4f86\u81ea<a href=\"https:\/\/www.bumc.bu.edu\/busm\/\" target=\"_blank\" rel=\"noopener\">School of Medcine<\/a>\u7684David Canaday \u8868\u793a\uff0c\u9ad8\u9f61\u65cf\u7fa4\u5c24\u5176\u4ee4\u4eba\u64d4\u6182\uff0c\u56e0\u70ba\u4ed6\u5011\u53ef\u80fd\u8eab\u9ad4\u865b\u5f31\u6216\u6709\u5176\u4ed6\u6162\u6027\u5065\u5eb7\u554f\u984c\u3002\u514d\u75ab\u7cfb\u7d71\u8f03\u5f31\u7684\u4eba\u4e5f\u53ef\u80fd\u4e0d\u6703\u5c0d\u75ab\u82d7\u63a5\u7a2e\u7522\u751f\u5f37\u70c8\u7684\u514d\u75ab\u53cd\u61c9\uff0c\u5f9e\u800c\u4f7f\u4ed6\u5011\u7684\u6297\u9ad4\u6c34\u6e96\u8f03\u4f4e\uff0c\u5982\u5668\u5b98\u79fb\u690d\u63a5\u53d7\u8005\u3001\u63a5\u53d7\u764c\u75c7\u6cbb\u7642\u4e2d\u6216\u670d\u7528\u6291\u5236\u514d\u75ab\u7cfb\u7d71\u85e5\u7269\u7684\u4eba\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u5728 CDC \u7814\u7a76\u4e2d\uff0c\u5728\u6574\u500b\u7814\u7a76\u671f\u9593\uff0c\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u7684\u4f4f\u9662\u60a3\u8005\uff0c\u75ab\u82d7\u6709\u6548\u6027\u70ba 63%\u3002\u9019\u5c31\u662f\u70ba\u4ec0\u9ebc CDC\u00a0<\/span><a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/recommendations\/immuno.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u63a8\u85a6<\/span><\/a><span style=\"font-weight: 400;\">\u00a0\u67d0\u4e9b\u5b8c\u5168\u63a5\u7a2e <strong>mRNA COVID-19<\/strong> \u75ab\u82d7\u7684\u4eba\u63a5\u7a2e\u75ab\u82d7\u52a0\u5f37\u5291\uff0c\u5b83\u662f\u91dd\u5c0d\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\u9019\u4ef6\u4e8b\u5be6\u800c\u7d66\u4e88\u7684\u3002\u65e8\u5728\u5e6b\u52a9\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u7684\u4eba\u5011\u9054\u5230\u8207\u5176\u4ed6\u4eba\u7fa4\u66f4\u63a5\u8fd1\u7684\u6297\u9ad4\u6c34\u6e96\u3002<\/span><\/p>\n<h2>\u7d50\u8ad6<\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u96d6\u7136\u570d\u7e5e COVID-19 \u75ab\u82d7\u7684\u8a0e\u8ad6\u6f38\u6f38\u8f49\u5411\u514d\u75ab\u529b\u53ef\u80fd\u6e1b\u5f31\u548c\u662f\u5426\u9700\u8981\u52a0\u5f37\u5291\uff0c\u4f46\u5df4\u96f7\u7279\u8aaa\uff1a\u300c\u4eba\u5011\u9700\u8981\u77e5\u9053\uff0c\u6700\u91cd\u8981\u7684\u662f\uff0c\u76ee\u524d\u4f7f\u7528\u7684\u6240\u6709COVID-19\u75ab\u82d7\u90fd\u6703\u7522\u751f\u5f37\u5927\u7684\u6297\u9ad4\u53cd\u61c9\uff0c\u9019\u7d55\u5c0d\u662f\u4fdd\u8b77\u81ea\u5df1\u514d\u53d7\u611f\u67d3\u7684\u6700\u4f73\u65b9\u5f0f\u3002\u300d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u53c3\u8003\u8cc7\u6599:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.nature.com\/articles\/s41586-019-0879-y\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Commonality despite exceptional diversity in the baseline human antibody repertoire. (n.d.). Nature. Retrieved October 29, 2021<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/academic.oup.com\/jid\/article\/224\/8\/1345\/6350267\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Determinants and Dynamics of SARS-CoV-2 Infection in a Diverse Population: 6-Month Evaluation of a Prospective Cohort Study. (n.d.). OXFORD. Retrieved October 29, 2021<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2021.08.15.21262067v3.full.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Significant reduction in humoral immunity among healthcare workers and nursing home residents 6 months after COVID-19 BNT162b2 mRNA vaccination. (n.d.). David H. Canaday. Retrieved October 29, 2021<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/recommendations\/immuno.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">COVID-19 Vaccines for Moderately to Severely Immunocompromised People. (n.d.). CDC. Retrieved October 29, 2021<\/span><\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u4e86\u89e3\u6297\u9ad4\u7684\u4fdd\u8b77\u539f\u7406\u4ee5\u53ca\u6297\u9ad4\u6c34\u6e96\u4e0b\u964d\u5c0d\u65bc\u9810\u9632\u65b0\u51a0\u80ba\u708e\u7684\u5f71\u97ff\u5f88\u91cd\u8981\u3002\u4f86\u4e86\u89e3\u6297\u9ad4\u751f\u6210\u7684\u539f\u56e0\u53ca\u75ab\u82d7\u7528\u4f55\u7a2e\u539f\u7406\u5c0d\u6297\u75c5\u6bd2\u3002<\/p>\n","protected":false},"author":19,"featured_media":47967,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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